Clinical Trials & Research

Researchers test the safety and efficacy of a natural anti-fungal treatment derived from spirulina to treat severe fungal infections of the skin and nails. Superficial fungal infections of the hair, skin, or nails, also referred to dermatophytosis, affects about a quarter of the world’s population. Topical anti-fungal treatment creams can be used to treat dermatophytosis,
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The NIH has amended its definition of clinical trials to include brain studies, introducing new regulations considered unnecessary by many researchers. The National Institutes of Health (NIH) has implemented its controversial decision to broaden the scope of clinical trials to include cognitive and behavioural studies. This change, which has been in discussion since at least
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Researchers determine whether oral corticosteroids, such as prednisolone,  reduce symptom duration or severity for acute lower respiratory tract infection in non-asthmatic adults. Acute lower respiratory tract infection (LRTI), defined as an acute cough with at least one of the symptoms of sputum, chest pain, shortness of breath, and wheezing is one of the most common
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Behavioural intervention can help decrease psychological distress among women with a history of gender-based violence. A clinical trial determines the effectiveness of a community-taught behavioral treatment on psychological distress. Gender-based violence toward women has been linked to increased mental stress and psychological morbidity in low and middle-income countries worldwide, specifically in urban Kenya. The treatment
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Given that the vast majority of opiate-dependent individuals relapse soon after detoxification, a recent study investigated whether the use of medications could assist in reducing the severity of opiate withdrawal. With over 11 million heroin users worldwide, the global health burden of opiate-dependent individuals remains high. Opiates are a class of drugs (including illicit drugs
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Despite the availability of chemotherapeutic agents for the treatment of acute lymphoblastic leukemia, some patients won’t respond to the drugs or experience relapse.  A phase 3 clinical trial examined the safety profile of inotuzumabozogazamin, a novel chemotherapeutic drug which has a potential to be used for relapsed and refractory acute lymphoblastic leukemia.   There are
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  In a 2017 study, researchers explored the risks and benefits of levothyroxine for subclinical hypothyroidism treatment in older adults. The findings suggest levothyroxine does not improve hypothyroidism symptoms.   Hypothyroidism – underproduction of the thyroid hormone thyroxine and compensatory overproduction of the pituitary hormone which promotes its release, thyroid-stimulating hormone (TSH) –can have profound
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Metabolic syndrome and non alcoholic fatty liver disease are conditions that are becoming more prevalent due to an increase of fructose and fats in our diets. A new study examines the role of citrulline in preventing endotoxin-induced injury in a rat model of non alcoholic fatty liver disease and finds that citrulline is able to prevent an inflammatory
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Tuberculosis is a communicable respiratory disease. A group of researchers led by Maeve Lalor conducted a cohort study to determine household transmission of tuberculosis in England by combining epidemiologic and molecular strain typing data.   Tuberculosis is a communicable respiratory disease prevalent in some third world countries. In first world countries where the prevalence of
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A recent study explored the antibacterial effects of modified forms of vancomycin on antibiotic-resistant bacteria. The results suggest C1-aminomethylene vancomycin may be an effective agent against methicillin-resistant Staphylococcus aureus (MRSA) and other antibiotic-resistant bacteria.   The ability of bacterial strains to acquire resistance to antibiotics faster than antibacterial therapies can be developed is of growing
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Polymeric micelles are an important class of targeted drug delivery systems that act as carriers of chemotherapeutic agents. A recent review summarized the research being carried out in the development and use of polymeric micelles and micelle-forming drug-polymer conjugates for cancer therapy.   A common problem in cancer treatment is the untargeted delivery of highly
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In case you missed it, here are the biggest headlines of the week! Effects of Mediterranean Diet on Endothelial Function and Blood Pressure A group of researchers conducted a randomized control trial to determine whether adherence to Mediterranean diet improved endothelial function and lowered blood pressure levels … [read more]   Is Ketamine with Electroconvulsive
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The Canadian government, under Prime Minister Justin Trudeau, plans on passing new legislation that will legalize recreational marijuana use across Canada for anyone over the age of 18. Despite wide public support, some policy makers and politicians have concerns regarding the logistics and wholesome regulation of recreational marijuana.   Legalizing recreational marijuana has been a
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A consultation paper proposing a risk-based approach to regulation of “self-care” products represents significant change in how cosmetics, natural health products and non-prescription drugs are regulated in Canada.   Health Canada is responsible for regulation of both prescription and non-prescription (or “self-care”) products sold in Canada.  Self-care products cover three categories of goods: Cosmetics, which
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Large scale nuclear disasters, such as in Fukushima and Chernobyl, have raised public concern over nuclear power and radiation exposure through medical procedures. However, most people are unaware that many household items and foods emit potentially dangerous radiation.   Public concern over radiation exposure has been heightened due to nuclear reactor accidents such as those
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