Aging

Researchers use data from large-scale postmenopausal studies to determine whether long-term bisphosphonate use is a good solution for preventing osteoporotic fractures. Osteoporosis is frequently associated with an increased risk of fracture due to a reduction in bone mineral density. About half of women over 50 years old are expected to experience an osteoporotic fracture. Bisphosphonates,
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Researchers examined the relationship between gait stability and physical activity in older adults performing treadmill exercises. Walking is a good physical activity, and previous studies have found that it provides improved gait stability in the elderly. As published in the European Review of Aging and Physical Activity, researchers recently used treadmill exercises to evaluate the
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Researchers study whether practicing tai chi – an ancient form of Chinese martial arts – might help older adults reduce their risk of accidental falls. Often referred to as a “moving meditation”, tai chi is an ancient Chinese practice that centers on developing flexibility and whole body coordination. The martial art had been previously reported
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Researchers from Toronto reveal an innovative approach to study brain changes linked to working memory loss in people with Alzheimer’s disease. Alzheimer’s Disease and Dementia Dementia is a general term for the loss of memory and other cognitive skills. Unlike cognitive impairment associated with normal aging, the cognitive decline associated with dementia is serious enough
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A recent study investigated whether there is a link between consuming high glycemic foods and the accumulation of amyloid-β plaques in older adults. More than one in eight Americans aged over 65 years is affected by Alzheimer’s disease, the most common form of dementia. The hallmark characteristic of Alzheimer’s disease is the formation and accumulation
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Researchers recently investigated whether there are racial differences found in the quality of end-of-life care in hospitals, hospices, or at home. Studies conducted in the United States assessing end-of-life care have shown that there may be differences in quality of care between races in the various areas of end-of-life care, including symptom management, communication, and
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A recent study investigated whether levels of brain atrophy in different subtypes of Alzheimer’s disease could be associated with different levels of education. Symptoms of brain atrophy, the shrinking of the brain which is caused by the loss of neurons, includes significant impairment to cognitive functions which can lead to Alzheimer’s disease dementia. Research has
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Researchers determine whether there is an association between aggressive treatment of hypertension and cognition function. Despite the relationship between hypertension and cognition being well established, recent concerns have arisen surrounding the treatment of hypertension. This concern is due to suspicions that more aggressive hypertension treatment, particularly in the elderly, may actually be linked to adverse
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In hopes to find a new treatment for Alzheimer’s, researchers determine if toxic tau tangles are the primary drivers responsible for the disease. The two pathological hallmarks of the devastating neurodegenerative disorder, Alzheimer’s disease, are amyloid plaques and tau protein tangles. Amyloid plaques and tau protein tangles are two brain abnormalities of Alzheimer’s disease. Amyloid
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A recent meta-analysis investigates whether sex, age, and a particular genotype are associated with a greater risk of developing Alzheimer’s disease. Alzheimer’s Disease (AD) is a chronic neurodegenerative condition, characterized by cognitive deficits in memory, thinking, and behaviour. Research has shown that different environmental, genetic, and socioeconomic cues can increase the risk of developing Alzheimer’s
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The relationship between memory and time has been studied extensively but is still poorly understood. A new study assessed memory and time deficits in Alzheimer’s disease (AD) patients in their home environments. It is widely accepted that as time passes, the ability to recall events and specific information declines. Episodic memory is the type of
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A recent analysis of geriatric patients hospitalized through emergency departments shows that proper geriatric assessments of older patients may reduce admission rates. A recent article published in Age and Ageing by the Oxford University Press reviewed the evidence behind performing comprehensive geriatric assessments (CGA) for more elderly patients that present at the emergency department. The
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In a recent study, researchers sought to identify proteins important for the anti-neural plasticity effects of histone deacetylase 2 (Hdac2) in Alzheimer’s disease. How Cells Control Gene Activity  Acetylation is one method by which cells control gene activity by the addition or removal of acetyl groups. Acetylation is performed by enzymes called acetyltransferases on histone
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Hydration health issues in the elderly have significant economic effects and while most elderly people recognize the importance of proper hydration, there may be limited health literacy including knowledge of signs and symptoms and health consequences of improper hydration. Dehydration is caused by excess fluid loss from the body and can lead to serious health
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Medication administration and management is a real problem in patients suffering from medical conditions associated with cognitive deficits. A recent study examined the experience of family members as they help take care of elder family members with Alzheimer’s disease. Compliance is an ongoing issue in medicine, particularly for elderly patients with medical conditions that cause
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A recently published study in Science determines whether it is possible for chimpanzees to develop Alzheimer ’s disease as they age. Alzheimer’s disease is a type of dementia that causes problems with cognition, behaviour, and memory. Alzheimer’s is a progressive, debilitating disease with no cure. The full diagnosis occurs when dementia is accompanied by two distortions
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In a 2017 study, researchers examined the relationship between rare gene variants and early-onset Alzheimer’s disease risk. Variants in a number of genes were identified, including PSD2, TCIRG1, and RIN3 – genes important to endolysosomal function. Mutations in a number of key genes have been implicated in the development of 5-10% of early-onset Alzheimer’s disease
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Tau proteins might be associated with dementia (including Alzheimer’s disease) as well as mild cognitive impairment and cognitive decline. The current study found that higher levels of total tau in blood plasma were significantly associated with cognitive decline. Dementia represents a broad category of neurological diseases that cause gradual cognitive decline over time. The most
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  Recently, the end of life care experienced by older adult individuals has sparked interest and observations have been made to identify the potential risk factors for aggressive care along with an evaluation of the cost. This highlights the need to keep families informed about what to expect when an older adult in their midst
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  Research examines the prevalence of abuse in older adults globally and in turn highlight the risk and need for increased protection services in this regard.   Elderly abuse continues to be a growing problem. In 2015 there were an estimated 901 million older adults, or adults over the age of 65, globally.  Psychological abuse
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  A recent article, published in The American Journal of Clinical Nutrition, investigates how the metabolism of eicosapentaenoic acid (EPA) and arachidonic acid (AA) changes with age.   There are significant metabolic and biological changes that occur with progressing age. These changes must be taken into consideration to maintain a healthy and balanced nutritional intake.
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Reducing maternal mortality rates has been a long-term goal of public health officials. In the past, the majority of research has focused on infant mortality and its relation to the mother’s age (maternal age), leaving the connection between maternal mortality rates and maternal age understudied. Recent research indicates that maternal mortality rates increase significantly after
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